Gene-Environment Interaction in Childhood Asthma
نویسندگان
چکیده
منابع مشابه
IL-23 Gene and Protein Expression in Childhood Asthma
Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. These changes are induced mostly by cytokines which are produced by T helper (Th) 2 cells. Recently, the role of interleukin-23 (IL-23) in the pathogenesis of adultallergic asthma has been studied. Objective: To explore IL...
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1 Wright RL. Malignant tumors in the spinal extradural space: results of surgical treatment. Ann Surg 1963; 157:227–231 2 Gilbert RW, Kim JH, Posner JB. Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Ann Neurol 1978; 3:40–51 3 Sorensen PS, Borgesen SE, Rohde K, et al. Metastatic epidural spinal compression: results of treatment and survival. Cancer 1990; 65:150...
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In this article, we discuss the relationship between environmental exposures within the school environment and pediatric asthma morbidity. This article will conclude by reviewing novel school based asthma education and therapeutic programs and environmental interventions designed to help mitigate pediatric asthma morbidity.
متن کاملGene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood.
BACKGROUND Regulatory T-cell dysfunction is associated with development of the complex genetic conditions atopy and asthma. Therefore, we hypothesized that single nucleotide polymorphisms in genes involved in the development and function of regulatory T cells are associated with atopy and asthma development. OBJECTIVE To evaluate main effects and gene-gene interactions of haplotype tagging si...
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Correspondence to: Dr M Kogevinas, Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Reseach (IMIM), 80 Dr Aiguader Rd, Barcelona 08003, Spain; [email protected] _________________________ A sthma is a complex disease with a diverse genetic and environmental component. Asthma shows a high level of phenotypic heterogeneity characterised by obstruction of the airway...
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ژورنال
عنوان ژورنال: International Journal of Immunopathology and Pharmacology
سال: 2011
ISSN: 2058-7384,2058-7384
DOI: 10.1177/03946320110240s409